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The practice of cannibalism in one Papua New Guinea tribe lead to the spread of Brain Bleeding Cannibal Core - Kuru - Epidemic fatal brain disease called kuru that caused a devastating epidemic in the group. But now, some members of the tribe carry a gene that appears to protect against kuru, as well as other so-called "prion diseases," such as mad cow, a new study finds.
The findings could help researchers better understand these fatal brain diseasesand develop treatments for people who have the diseases, the researchers said. The Papua New Guinea tribe, known as the Fore people, used to conduct a funeral ritual that involved consuming the human brain.
Early in the 20th century, tribe members began to develop kuru, a neurological disorder caused by infectious prionswhich are proteins that fold abnormally and form lesions in the brain. This was the start of an epidemic of kuru among the Fore people, which at its peak in the s, killed Brain Bleeding Cannibal Core - Kuru - Epidemic to I Have The Touch (1983 Remix) - Peter Gabriel - Shaking The Tree: Sixteen Golden Greats percent of the tribe each year.
The tribe stopped practicing cannibalism in the late s, which lead to a decline in kuru. But because the disease can take many years to show Brain Bleeding Cannibal Core - Kuru - Epidemiccases continued to appear for decades. Recently, researchers discovered that some of the people who survived the kuru epidemic carry a genetic mutation called V, whereas those who developed kuru did not have this mutation. This led the researchers to suspect that V conferred protection against the disease.
In a new study, researchers genetically engineered mice to have the V mutation, and then injected the animals with infectious prions. Results showed Dont Cry My Angelina - Val Doonican - Gentle On My Mind mice with one copy of the V mutation were resistant to kuru, as well as a similar disease called classical Creutzfeldt-Jakob disease.
Mice with two copies of V were resistant to those diseases, as well as another prion disease, called variant Creutzfeldt-Jakob diseasewhich is sometimes referred to as the "human form of mad cow disease. Although the cessation of cannibalism among the Fore people led to a decline in kuru cases, the new study suggests that if the disease had continued to spread, the "region might have been repopulated with kuru-resistant individuals," the researchers wrote in the June 10 issue of the journal Nature.
It's important to note Forward Natty - Al Campbell - Forward Natty the practice of cannibalism did not directly lead to development of resistance to kuru. Rather, this mutation was likely present in the population before the kuru epidemic, but it became much more common when it provided a genetic advantage — that is, people with the mutation were able to survive kuru.
Such selection of genetic The OJays - Message In Our Music is the basis of evolution. John Collinge, the senior author of the study and a professor of neurodegenerative disease at University College London, said in a statement. The genetic mutation appears to prevent prion proteins from changing shape. Understanding exactly how the mutation does this could lead to new insights into how to prevent prion disease, the researchers said.
Follow Rachael Rettner RachaelRettner. Original article on Live Science. Live Science. This photo shows the brain tissue of someone with variant Creutzfeldt-Jakob disease vCJDwhich is caused by abnormal proteins called prions. The disease is believed to have a long incubation period, of many years, but is ultimately fatal.
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